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    Denso 5334381 - Oxygen Sensor Set
    • Free shipping

          Denso 5334381 - Oxygen Sensor Set

          MPN: 5334381
          0.0
          Vehicle Specific
          Check if this part fits your vehicle.
          • $162.95
          In stock

          Product Overview

          The Denso 5334381 Oxygen Sensor Set is designed to monitor and regulate the oxygen levels in your vehicle’s exhaust system, ensuring optimal engine performance and reduced emissions. This part offers OE-level quality, reliability, and a precise fit for various Cadillac, Chevrolet, and GMC models. Trust in the Denso brand to deliver exceptional performance and durability for your vehicle. Choose Denso 5334381 for dependable performance and peace of mind every time you service your vehicle.

          Cross Reference Numbers

          This Denso 5334381 is equivalent to or replaces the following part numbers: 12563345, 25312194, 19209817, 19178958, 19178116, 19178935, 12616672, 25312211, 12565414, 25315373, 25312201, 12563346, 19178945, 12565397, 5334381Kit, AFS135, AFS109, OS2010, 21539, ES20088, 13474, 350-34596, 35034596, 250-24248, 25024248, 21513, AFS95, AFS125, SG534, 213-4253, 2134253, SG272, SG280, 213-939, 213939, 350-34525, 35034525, AFS106, 213-922, 213922, 250-24018, 25024018, ES20000, OS839, ES20383, 13686, OS824, OS216, ES20001, 213-921, 213921, 213-941, 213941, OS823.

          Vehicle Compatibility

          • Cadillac 2002 Escalade 6.0 V8
          • Cadillac 2002 Escalade EXT 6.0 V8
          • Chevrolet 2000 C2500 7.4 V8
          • Chevrolet 2000 C3500 7.4 V8
          • Chevrolet 2000 K2500 7.4 V8
          • Chevrolet 2000 K3500 7.4 V8
          • GMC 2001-2002 Yukon 6.0 V8
          • Chevrolet 2000 C2500 7.4 V8
          • Chevrolet 2000 C3500 7.4 V8
          • Chevrolet 2000 K3500 7.4 V8

          This also fits other applications. Please use the vehicle selector tool to verify fitment.

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          Frequently Asked Questions

          What is the function of the Denso 5334381 Oxygen Sensor?

          The Denso 5334381 Oxygen Sensor measures the level of oxygen in the exhaust gases, helping to optimize fuel efficiency and reduce harmful emissions.

          What are some common DTCs associated with oxygen sensors?

          Common Diagnostic Trouble Codes (DTCs) related to oxygen sensors include P0130, P0131, P0132, P0133, P0134, P0135, P0136, P0137, P0138, and P0139.

          How do I know if I need to replace my oxygen sensor?

          If you notice a decrease in fuel efficiency, increased emissions, or your check engine light is on, it may be time to replace your oxygen sensor with the Denso 5334381.

          Can I install the Denso 5334381 myself?

          Yes, with the right tools and knowledge, you can install the Denso 5334381 Oxygen Sensor yourself. However, if you're uncertain, it is advisable to seek professional assistance.

          Why should I purchase the Denso 5334381?

          Order Denso 5334381 today for a factory-correct replacement that restores safety and performance.

            • Newparts SKU
              5334381
            • Weight
              1 lbs
            • Manufacturer Part #
              5334381
          • Brand
            Denso
          • Manufacturer
            Denso
          • MPN
            5334381-Kit
          • Features
            Connector Gender : (Downstream Oxygen Sensor) Female
            Connector Gender : (Upstream Oxygen Sensor) Female
            Mounting Type : (Downstream Oxygen Sensor) Threaded
            Mounting Type : (Upstream Oxygen Sensor) Threaded
            Sensor Type : (Downstream Oxygen Sensor) Heated
            Sensor Type : (Upstream Oxygen Sensor) Heated
            Universal Or Specific Fit : (Downstream Oxygen Sensor) Specific
            Universal Or Specific Fit : (Upstream Oxygen Sensor) Specific
            Wire Quantity : (Downstream Oxygen Sensor) 4
            Wire Quantity : (Upstream Oxygen Sensor) 4
            Wiring Harness Length : (Downstream Oxygen Sensor) 15.35
            Wiring Harness Length : (Upstream Oxygen Sensor) 14.76
          • OE Part Numbers
            12563345, 25312194, 19209817, 19178958, 19178116, 19178935, 12616672, 25312211, 12565414, 25315373, 25312201, 12563346, 19178945, 12565397
          • Cross Reference Numbers
            5334381Kit, AFS135, AFS109, OS2010, 21539, ES20088, 13474, 350-34596, 35034596, 250-24248, 25024248, 21513, AFS95, AFS125, SG534, 213-4253, 2134253, SG272, SG280, 213-939, 213939, 350-34525, 35034525, AFS106, 213-922, 213922, 250-24018, 25024018, ES20000, OS839, ES20383, 13686, OS824, OS216, ES20001, 213-921, 213921, 213-941, 213941, OS823
          • Part Type
            Oxygen Sensor Set
          • Kit Content
            2 x Denso - (234-4018) Downstream Oxygen Sensor - OE Style
            2 x Denso - (234-4103) Upstream Oxygen Sensor - OE Style
          • Fitment
            • Fitment Type
              Vehicle Specific
          YearMakeModelSubmodelNotes
          2002CadillacEscaladeBase (6.0 V8 GAS)VIN: N, Transmission Control: Automatic, Transmission Code: 4L60-E, Transmission Code: 4L80-E, Transmission Code: 4L60-E-HD
          2002CadillacEscalade EXTBase (6.0 V8 GAS)VIN: N, Transmission Control: Automatic, Transmission Code: 4L80-E, Transmission Code: 4L65-E, Transmission Code: 4L60-E-HD
          2002GMCYukonDenali (6.0 V8 GAS)VIN: U, Transmission Control: Automatic, Transmission Code: 4L60-E
          2000ChevroletC2500Base (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletC2500LS (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletC3500Base (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletC3500LS (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletK2500Base (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletK2500LS (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletK3500Base (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000ChevroletK3500LS (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC2500Sierra SL (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC2500Sierra SLE (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC2500Sierra SLT (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC3500Sierra SL (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC3500Sierra SLE (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCC3500Sierra SLT (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCK3500Sierra SL (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCK3500Sierra SLE (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2000GMCK3500Sierra SLT (7.4 V8 GAS)VIN: J, Transmission Control: Automatic, Transmission Control: Manual, Transmission Code: 4L80-E, Transmission Code: NV4500/MW3, Notes: Exclude California
          2001GMCYukonDenali (6.0 V8 GAS)VIN: U, Transmission Control: Automatic, Transmission Code: 4L60-E, Transmission Code: 4L80-E
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          Warranty Overview

          At Newparts, we stand behind the quality of the products we sell. Every part we offer is backed by a warranty designed to give you peace of mind and protect your investment.

          Standard Warranty – Most Parts

          • Coverage: 2 years or 24,000 miles (whichever comes first) from purchase date.

          • Protection: Defects in materials or workmanship under normal personal use.

          • Eligibility: Applies only to the original purchaser and the vehicle where the part was first installed.

          • Exclusions:

            • Wear-and-tear items (brake pads, filters, bulbs, wipers, etc.)

            • Commercial, fleet, rideshare, off-road, or racing use

            • Improper installation, misuse, accidents, or modifications

          • Not Covered: Labor, shipping, towing, or incidental costs.

          Bison Performance Warranty – Our House Brand

          • Coverage: Limited Lifetime Warranty for as long as you own your vehicle.

          • Applies To: All products sold under the Bison Performance label.

          • Premium Protection: Goes beyond our standard warranty — if it’s a Bison product, the 2-year/24k mile limit is replaced with lifetime coverage.

          • Exclusions: Same as the standard warranty (normal wear, commercial use, improper installation, etc.).

          • What’s Included: Replacement of the defective product (labor and shipping excluded).

          Warranty Claim Requirements

          To keep claims fast and fair, we require:

          • Proof of purchase (invoice or order confirmation).

          • Photos or videos showing the defective part, order number, date, VIN, and odometer reading.

          • Diagnostic reports or part returns for non-visible issues may be requested.

          • Claims must be truthful, properly documented, and reflect normal consumer use.

          Buy With Confidence: We back our products because we believe in their quality, with a transparent, customer-first warranty process you can trust. And with Bison Performance products, you’ll enjoy Limited Lifetime protection—an assurance few brands can match.

          For full details and exclusions, please see our complete Warranty Terms & Conditions.


          This summary is for convenience only. For full warranty coverage details, exclusions, and requirements, see our official Warranty Terms & Conditions. In case of conflict, the full policy governs.

          Return Policy Overview

          Most parts can be returned within 30 days of delivery if unused, uninstalled, and in original packaging.
          To start a return, use our Return Portal or contact support.

          • Restocking fee: Up to 20% may apply for certain orders (buyer’s remorse, order errors, or special-order items)

          • Refunds: Issued to your original payment method within 3–5 business days after inspection

          • Exchanges: Not automatic — please return and reorder

          • Replacements: May be approved for incorrect or defective items reported within 7 days

          Not returnable:

          • Used or installed parts

          • Electrical components

          • Opened filter kits, gaskets, or contaminated items

          • Final sale or custom orders

          Important Notes:

          • Return shipping is your responsibility unless we made a verified error

          • Fitment is the customer’s responsibility (we can assist, but do not guarantee)

          • Country of origin may vary and is not grounds for return

          For complete details, please see our full Return Policy.



          This Returns summary is provided for convenience only. All returns, refunds, and exchanges are subject to the complete Returns Policy. In the event of any conflict, the full policy governs.

          Fast, Reliable Shipping — Straight to Your Door

          We ship most orders the same day when placed before 2 PM CST (Monday–Friday). Our main warehouse is just east of Nashville, TN, and we also ship from multiple locations nationwide to get your order to you as quickly as possible.

          • We use trusted carriers like UPS, FedEx, and USPS.

          • Tracking info is emailed to you as soon as your order ships.

          • Delivery estimates at checkout are based on carrier data, but not guaranteed.

          Need help with a shipment?

          If your order is missing, damaged, or incorrect, just let us know within 5 days of delivery. We’ll walk you through the quick claim process — including a few photos to help us make things right.

          For full details, please see our complete Shipping Policy.


          This Shipping summary is provided for convenience only. Delivery times, carrier terms, fees, restrictions,  risk of loss, and other details are governed by our complete Shipping Policy. In the event of any conflict, the full policy governs.

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